課程資訊
課程名稱
生技製藥二
Pharmaceutical Biotechnology (Ⅱ) 
開課學期
100-1 
授課對象
學程  分子醫藥學程  
授課教師
 
課號
PHARM5007 
課程識別碼
423 U0540 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期五6(13:20~14:10) 
上課地點
 
備註
必須同時修習生技製藥一。
總人數上限:18人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1001pharma_2 
課程簡介影片
 
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課程概述

This is the second part of a half-year survey course aimed to introduce Pharmacy students to various biotechnology-related techniques and their applications in the discovering and manufacturing of biopharmaceuticals as well as biomedical research. The course begins with a general introduction to the physicochemical characteristics, pharmacology, and formulation of proteins and the basics in protein production and manufacturing. Since the production, downstream processing, and characterization of biopharmaceuticals are in many aspects very different from conventional small molecular therapeutics, issues relevant to the handling and delivering of those products are also highlighted. Finally, several approved and potential biopharmaceuticals are discussed. Two hours of lecture per week.
 

課程目標
To introduce Pharmacy students to various biotechnology-related techniques and their applications in the discovering and manufacturing of biopharmaceuticals as well as biomedical research  
課程要求
 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
 
參考書目
References:
1. (CS) D. J.A. Crommelin, R.D. Sindelar (2002), Pharmaceutical Biotechnology — An Introduction for Pharmacists and Pharmaceutical Scientists, Hardwood Academic Publishers
2. (KM) O. Kayser, R.H. Muller (2004), Pharmaceutical Biotechnology — Drug Discovery and Clinical Applications, Wiley-VCH  
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
Class participation 
10% 
 
2. 
Written Report/Oral Presentation 
30% 
 
3. 
Written Exams 
60% 
one final 
 
課程進度
週次
日期
單元主題
第10週
11/18  Gene Therapy
Chapter 7 (CS), Chapters 13 and 14 (KM) 
第11週
11/25  Hybridoma Technology & Applications in the Production of Monoclonal Antibodies
Chapter 13 (CS) 
第12週
12/02  Biotechnologically Derived Therapeutic Proteins: insulin, monoclonal antibodies, Chapter 10 (Insulin), Chapter 13 (Monoclonal Antibody-based pharmaceuticals) 
第13週
12/09  Chapter 12 (Vaccines) 
第14週
12/16  Chapter 14 (Recombinant Thrombolytic Agents), Chapter 15 (Recombinant Coagulation Factors) 
第15週
12/23  Biotechnology Products in the Pipeline
Chapter 20 (CS)
 
第16週
12/30  Group Discussion/Presentation 
第17週
1/06  Group Discussion/Presentation